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"The project of CCP PERIMED will be implemented by 4 partners:

  1. Medical University - Plovdiv (lead partner)
  2. Plovdiv University ""Paisii Hilendarski""
  3. Institute of Mineralogy and Crystallography at the Bulgarian Academy of Sciences
  4. Perimed-2 Association (new partner)

The project will implement 3 activities:

  1. Research and dissemination of scientific results
  2. Construction and/or modernisation of research infrastructures and equipment necessary for carrying out research
  3. Training and mobility of researchers

The scientific programme of the project includes 10 work packages (WPs):

  1. Intestinal microbiome – potential for prevention of colorectal cancer. Genetic monitoring of breast cancer
  2. Diagnostic and prognostic genetic markers and therapeutic targets in patients with malignant myeloproliferative diseases
  3. Phytopharmaceutical Strategies and Biotherapists in Personalized Medicine
  4. Development of a complex modern methodology for specialized molecular genetic and flow cytometric monitoring of minimal residual disease in children with acute lymphoblastic leukaemia
  5. Causal analysis based on databases and personalized management of a critically ill patient
  6. Molecular biomarkers of the human microbiome
  7. Immunomodulation, cytotoxicity and selective antitumor activity. Immunopreparations
  8. Biopolymers, nanomaterials and biologically active substances
  9. Biocatalysis and biosensors
  10. Physico-chemical control of innovative pharmaceutical forms and active pharmaceutical ingredients

The expected results of the project implementation are:

  • Increased capacity to carry out research in personalised medicine Protected industrial property rights, part of which through technology transfer will be realized in practice in the industry
  • Improved collaboration between scientific organisations in the field of personalised diagnostics, therapy and medical care"

Center type

Competence Center "Personalized Innovative Medicine (PERIMED)"

Regions

Plovdiv

Municipalities

Plovdiv

City

Plovdiv

Address

Bulgaria, Plovdiv, 4002, 15A Vasil Aprilov Blvd.

Cellular sorter based on 4 laser multiparameter flow cytrometry, MAKE: BD FACSAria III, Model:BD FACSAria III cell sorter 4 laser AC DU 6B/3R/6V/2UV

Software for integration of information flows from different monitoring devices and results of laboratory tests of patients from the hospital information system /BIS/.

Next Generation Nucleic Acid Sequencing System, Illumina Inc. MiSeq Sistem

Transmission electron microscope with microtome for preparation of samples of biological origin, Model: Talos F200C TEM 2. Scanning electron microscope with X-ray microanalyzer, Model: prisma E SEM 3. Chromatographic system for high performance liquid chromatography, Model: Thermo Scientific Dionex UltiMate 3000

Automatic flow-through system for determination of reconstitution according to USP4, Model:CE 7smart 2. Nano Sputtering Dryer, Model: B-90 HP, Advanced 3. Encapsulator, Model: B-395 Pro

Next generation personal desktop sequencing based on the principle of sequencing through synthesis, Model: MiSeq

Patient monitor for vital signs monitoring. Brand: DRAEGER.

Bioimpedance tomography device for pulmonary function assessment. Brand: Bodystat, model: Multiscan 5000.

Bioimpedance tomography system for lung examination. Brand: SWISSTON, model: BB2.

Clinical flow cytometer capable of measuring 14 parameters. Model: BD FACSLyric.

Published on: 01.10.2025